Mario Archila-Meléndez

mario-copy

Mario Archila-Meléndez

Position
Ph.D. Student
Core research topics
Language perception, Epilepsy, Functional brain surgery, Brain-computer interfaces

My main interests are the neurophysiological basis of human cognition and its role in brain pathology, and the translation of fundamental neuroscience research into clinical and neurosurgical applications by the implementation of new technologies, such as robotics and machine learning, in the treatment of neurosurgical pathologies.

During my Master’s, under the supervision of Prof. Bernadette Jansma, I studied the effects of cross-modal integration (e.g., in the superior temporal and fusiform gyri) of familiar voices and faces, using functional magnetic resonance imaging (fMRI) at 3T and multivoxel pattern analysis (MVPA). Currently, I am working with the departments of Neurology and Neurophysiology from Maastricht University Medical Centre (MUMC+) and the department of Cognitive Neuroscience. Our project seeks to understand the neural processing during speech perception. First, by using 7T fMRI in combination with MVPA, we analyze the cortical spatial representation of speech features and the modulatory effect of attention in these representations. And second, by using advanced coherence, cross-frequency coupling, and classification analysis techniques of intracranial electrophysiological signals from patients with refractory epilepsy, we explore the evolution of the spectro-temporal representations of speech features during attention.